Based on marquis1 data we predicted an average 29 medication discrepancies per patient with a poisson distribution17 allowing for detection of a reduction to 24 discrepancies per patient during the intervention at a single site with 82 power and 5 type 1 error implementation of an intervention at two sites allowed for detection of changes from 29 to 26 discrepancies per patient. Most burn centers use a modified parkland formula to calculate total fluid volume requirements taking into account tbsa and the patients body weight see parkland formula this formula helps determine fluid needed from loss and shifts related to the injury as well as insensible losses and loss through nonintact skin after a total volume is calculated half of that volume is given in . Former mstf chair douglas rex md professor emeritus of medicine at the indiana university school of medicine observed in an interview that the accumulated evidence doesnt clearly point out what the targets should be but added that it does give something of a guide to make a reasonable recommendation
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